CUSTOMIZED CONTRACT RESEARCH AVAILABLE AT ANTICANCER INC. Topical selective delivery of liposome-lacZ gene to hair follicle of mice. Lingna Li ... AntiCancer Inc. discovers new source of stem cells in hair follicle that repairs nerve and spinal cord injury - Video Presentation [33 Mb, 13:25 min] Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction (video) Topical liposome hair follicle targeting Screening Service for Hair Follicle Modifiers ° Small and large molecule delivery Hair Growth Stimulators and Inhibitors ° Gene delivery Inhibitors of Chemotherpay Induced Alopecia ° 5-a-reductase inhibitor delivery Hair Pigment Modifiers ° Protein delivery Acne Inhibitors CUSTOMIZED CONTRACT RESEARCH AVAILABLE AT ANTICANCER INC. Topical selective delivery of liposome-lacZ gene to hair follicle of mice Lingna Li and Robert M. Hoffman: The feasibility of targeted selective gene therapy of the hair follicle. Nature Medicine, 1, 705-706, 1995 Blue color indicates lac-Z gene expression in the matrix cells of hair follicle bulb, magnification: a) 400X, b) 1000X HAIR SHAFTS GENETICALLY MODIFIED WITH GFP GROWING IN MICE SOURCE: Proceedings of the National Academy of Sciences 2002;10.1073/pnas.192453799./Saito, N., Zhao, M., Li.L., Baranov, E., Yang, M., Ohta, Y., Katsuoka, K., Penman, S., and Hoffman R.M. High efficiency genetic modification of hair follicles and growing hair shafts. Proc. Natl. Acad. Sci USA 99, 1310-1314, 2002. IN VITRO HISTOCLTURE HAIR GROWTH ASSAY Hair growth with progressing pigment production from anagen-induced C57 Bl-6 mouse skin
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